Book recs with themes about loneliness and isolation, eternal life, living many lives, reincarnation, alternate timelines, and/or choosing something/someone despite the circumstances?

It can be in any kind of setting. Lately, I’ve been resonating with stories about feeling alone and isolated, feeling out of place, and thinking about other possibilities born out of the different choices we make. I am also a fan of reincarnation and alternate lives plot lines. I have read The Invisible Life of Addie Larue and really enjoyed it. I also tend to resonate with misunderstood characters and those who suffer in silence.