Science and Social Studies a step above “Popular”

I've read a lot of non fiction over the years, and I'm finding myself wanting to dive into some excellent non-fiction. Science in particular, but I'm open to basically anything.

But I want something with a bit more depth than a typical pop sci or similar. No Freakonomics or Malcolm Gladwell, for example.

I recently read The Vital Question (Nick Lane), and it nailed the right level for me. Another example from the softer sciences is Capital (Thomas Piketty).

I have an engineering education and so I'm more well versed in science and math than most. But I'd also be very interested in excellent biographies, history, etc.

Thanks!