Like not the usual setting (haunted house, serial killer, paranormal being growing in power, ragtag group trying to survive something). Sphere comes to mind but I'm sure there are even more unique ones out there because that's still a group of scientists and strange things happening which is a trope too. I love horror stories but they usually fall into the same setups. Even Steven King stories as different as they are tend to unfold in a similar way
by floatable_shark